周伯琦（1298年 - 1369年）字伯溫，饒州人。元代官員、書法家。曾任南海縣主簿，後升為翰林院修撰。元順帝至正元年，由修撰特例拜為宣文閣授經郎、鑒書博士，轉經筵官、崇文監丞，以南人出身而于至正十二年四月由翰林直學士、兵部侍郎拜監察御史，陪同皇帝巡幸上都。其升轉的原由則是當年二月下達的聖旨，禁止任官時的種族歧視現象。伯琦特別擅長篆書，為當時篆書名家。曾在元仁宗時期的宣文閣供職，受到書法家康里巙巙的讚揚。據楊士奇的記載，巙巙稱：「周伯琦篆書，今世無過之者。」其篆書作品《相鶴經》今藏于國立故宮博物院。

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Zhou Boqi 周伯琦 (1298–1369) was a Chinese court poet during the Yuan Dynasty. Zhou was born in Raozhou (now Boyang) but grew up in Beijing, and in his early career worked there as a magistrate and later as Senior Compiler for Imperial Academy. He was well known for his seal script calligraphy.